aseptic filling

At ISOFLOW, we deliver advanced containment solutions engineered to meet the exacting standards of pharmaceutical aseptic filling. Our small volume aseptic filling isolator systems are designed for both hazardous and non-hazardous applications, ensuring cGMP compliance while maximizing safety and efficiency. Trusted by industry leaders like IntasPharma and Pharmidea, ISOFLOW’s isolators provide a reliable, turnkey solution for small-scale manufacturing and filling processes. Explore how our technology can enhance your aseptic operations.

Aseptic Filling Isolators: Precision and Safety

ISOFLOW’s aseptic filling isolators are purpose-built to handle small volume production with uncompromising sterility and operator protection. Our flagship system, the C4 Model (4′ with 2 Gloves and 1 Antechamber Transfer), offers a compact yet powerful solution for cGMP-compliant aseptic filling. Key features include:

Multiple Glove Design: Integrates seamlessly with small volume aseptic filling equipment for precise handling.
ISO 5 Unidirectional Airflow: Maintains a sterile environment with consistent, contamination-free air circulation.
316 Stainless Steel and Tempered Glass Construction: Ensures durability, visibility, and compliance with pharmaceutical standards.
Inflatable Seals: Provides an airtight workspace for all transfer operations.
H2O2 Decontamination Integration: Delivers fast, effective sterilization cycles.
Alpha Beta Doors: Enhances secure material transfer.
BIBO (Bag-In/Bag-Out) Exhaust Filtration: Safely manages hazardous filling with a fully exhausted system.

The C4 model’s mobility makes it ideal for material transfers, while its modular design—featuring partially assembled panels and structures—allows for easy on-site assembly over existing filling lines, minimizing disruption to your facility.

Advanced Technology for Optimal Performance

ISOFLOW isolators are equipped with cutting-edge features to streamline aseptic filling processes. Our H2O2 (hydrogen peroxide) decontamination system ensures rapid cycles and fast recovery rates, with a single Allen Bradley HMI/PLC controlling both the isolator and H2O2 generator. This integrated approach enables efficient decontamination across multiple units, including compatibility with our larger C8 model.

For hazardous filling applications, the BIBO filtration system provides a fully exhausted setup, safely containing and removing contaminants. As a turnkey solution, ISOFLOW handles everything—equipment integration, interfacing, start-up, training, and full validation (IQ/OQ/PQ)—ensuring your operation meets cGMP standards from day one.

Why ISOFLOW for Aseptic Filling?

Proven Expertise: Trusted by IntasPharma and Pharmidea for small volume aseptic filling.
Hazardous Material Safety: BIBO filtration and exhausted systems protect personnel and the environment.
Flexible Installation: Modular construction adapts to your existing filling line.
Comprehensive Support: End-to-end service from integration to validation.

ISOFLOW’s aseptic filling isolators combine precision engineering with practical design, offering a reliable solution for small-scale pharmaceutical manufacturing. Contact us at 1-800-849-3429 to learn how we can support your aseptic filling needs with industry-leading containment technology.